Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Ppn
Flybase description The gene Papilin is referred to in FlyBase by the symbol Dmel\Ppn (CG33103, FBgn0003137).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -13.214 2.6656 -2.579694 -0.4347 -5.406677 -1.8706 -18.58967 -2.813946
    Affimetrix absolute value 4.922 8.999 6.861 8.258 6.347 7.664 4.341 6.886
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: extracellular matrix structural constituent.
There is experimental evidence that it is involved in the biological process: extracellular matrix organization.
8 alleles are reported.
The phenotypes of these alleles are annotated with: Malpighian tubule; embryonic/larval tracheal system; embryonic/larval somatic muscle.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: ADAM-TS Spacer 1; Immunoglobulin I-set; Immunoglobulin subtype 2; Immunoglobulin-like; Immunoglobulin-like fold; PLAC; Peptidase M12B, ADAM-TS; Proteinase inhibitor I2, Kunitz metazoa; Proteinase inhibitor I2, Kunitz, conserved site; Thrombospondin, type 1 repeat; Whey acidic protein, 4-disulphide core.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression.
Peak expression observed within 12-24 hour embryonic stages.
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