Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name prd
Flybase description The gene paired is referred to in FlyBase by the symbol Dmel\prd (CG6716, FBgn0003145).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -57.5312 -32.1574 -49.59624 -55.4941 -79.28538 -61.0992 -64.24897 -56.420666
    Affimetrix absolute value 2.564 2.626 2.57 2.599 2.463 2.631 2.551 2.5
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: positive regulation of transcription, DNA-dependent.
73 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system; organ system subdivision; cuticle; abdominal ventral denticle belt; embryonic/larval neuron; larval abdominal segment; thoracic segment; peripheral nervous system; metathoracic ventral denticle belt; gland; nervous system; adult; heart primordium; embryonic segment; epithelial furrow; external compound sense organ; syncytial blastoderm embryo; antennal segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related; Paired box protein, N-terminal; Winged helix-turn-helix transcription repressor DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages, in adult male stages.
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