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Gene name | Pu | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Punch is referred to in FlyBase by the symbol Dmel\Pu (CG9441, FBgn0003162). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: GTP cyclohydrolase I regulator activity; GTP cyclohydrolase I activity. There is experimental evidence that it is involved in the biological process: preblastoderm mitotic cell cycle; regulation of GTP cyclohydrolase I activity; cuticle pigmentation; pteridine biosynthetic process; regulation of epithelial cell migration, open tracheal system; embryonic pattern specification; compound eye pigmentation; larval chitin-based cuticle development. 80 alleles are reported. The phenotypes of these alleles are annotated with 11 unique terms, many of which group under: organ system; organ system subdivision; cuticle; extended germ band embryo; multicellular structure; adult segment; adult mesothoracic segment; integumentary system; blastoderm embryo; acellular anatomical structure; somatic cell; sensillum; cephalopharyngeal skeleton; external compound sense organ. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: GTP cyclohydrolase I; GTP cyclohydrolase I, conserved site; GTP cyclohydrolase I/Nitrile oxidoreductase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed during late larval stages, at stages throughout the pupal period. . |