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| Gene name | pum | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene pumilio is referred to in FlyBase by the symbol Dmel\pum (CG9755, FBgn0003165). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: translation repressor activity, nucleic acid binding; mRNA 3'-UTR binding. There is experimental evidence that it is involved in the biological process: regulation of synaptic transmission; synaptic transmission; dendrite morphogenesis; pole cell migration; long-term memory; head involution; regulation of synaptic growth at neuromuscular junction. 134 alleles are reported. The phenotypes of these alleles are annotated with 41 unique terms, many of which group under: embryonic abdomen; organ system; organ system subdivision; embryonic segment; female germline cyst; peripheral nervous system; germarium; embryonic/larval neuron; cephalopharyngeal skeleton; portion of tissue. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Armadillo-like helical; Armadillo-type fold; Pumilio RNA-binding repeat. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. . |
