Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name r
Flybase description The gene rudimentary is referred to in FlyBase by the symbol Dmel\r (CG18572, FBgn0003189).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.651 -9.2443 -12.649098 -10.4991 -17.653955 -14.1428 -18.58698 -14.913305
    Affimetrix absolute value 4.187 4.42 4.543 5.059 4.626 4.762 4.352 4.35
    Affymetric present call in "x" number of chips 0 2 1 3 1 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: dihydroorotase activity; aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity.
There is experimental evidence that it is involved in the biological process: 'de novo' pyrimidine base biosynthetic process; glutamine metabolic process.
269 alleles are reported.
The phenotypes of these alleles are annotated with: ovary; wing margin bristle; wing vein L4; posterior wing margin; wing; wing vein.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Amidohydrolase 1; Aspartate carbamoyltransferase, eukaryotic; Aspartate/ornithine carbamoyltransferase; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Carbamoyl-phosphate synthase, GATase domain; Carbamoyl-phosphate synthase, large subunit; Carbamoyl-phosphate synthase, large subunit, CPS-domain; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthase, small subunit; Carbamoyl-phosphate synthase, small subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Dihydroorotase, conserved site; Glutamine amidotransferase type 1; Metal-dependent hydrolase, composite domain; Methylglyoxal synthase-like domain; Pre-ATP-grasp fold; PreATP-grasp-like fold.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages.
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