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Gene name | r | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene rudimentary is referred to in FlyBase by the symbol Dmel\r (CG18572, FBgn0003189). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: dihydroorotase activity; aspartate carbamoyltransferase activity; carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity. There is experimental evidence that it is involved in the biological process: 'de novo' pyrimidine base biosynthetic process; glutamine metabolic process. 269 alleles are reported. The phenotypes of these alleles are annotated with: ovary; wing margin bristle; wing vein L4; posterior wing margin; wing; wing vein. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ATP-grasp fold; ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Amidohydrolase 1; Aspartate carbamoyltransferase, eukaryotic; Aspartate/ornithine carbamoyltransferase; Aspartate/ornithine carbamoyltransferase, Asp/Orn-binding domain; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding; Carbamoyl-phosphate synthase, GATase domain; Carbamoyl-phosphate synthase, large subunit; Carbamoyl-phosphate synthase, large subunit, CPS-domain; Carbamoyl-phosphate synthase, large subunit, N-terminal; Carbamoyl-phosphate synthase, small subunit; Carbamoyl-phosphate synthase, small subunit, N-terminal; Carbamoyl-phosphate synthetase, large subunit, ATP-binding; Carbamoyl-phosphate synthetase, large subunit, oligomerisation; Dihydroorotase, conserved site; Glutamine amidotransferase type 1; Metal-dependent hydrolase, composite domain; Methylglyoxal synthase-like domain; Pre-ATP-grasp fold; PreATP-grasp-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, during early pupal stages, in adult female stages. . |