Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name rdgB
Flybase description The gene retinal degeneration B is referred to in FlyBase by the symbol Dmel\rdgB (CG11111, FBgn0003218).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -0.4119 -2.8546 -9.950146 -4.1786 -8.93017 -5.6968 -6.35981 -6.010917
    Affimetrix absolute value 8.306 6.143 4.912 6.33 5.622 6.059 5.885 5.676
    Affymetric present call in "x" number of chips 3 3 2 3 1 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: phosphatidylcholine transmembrane transporter activity; phosphatidylinositol transporter activity.
There is experimental evidence that it is involved in the biological process: rhodopsin mediated signaling pathway; phototransduction; phosphatidylinositol metabolic process; deactivation of rhodopsin mediated signaling; sensory perception of smell.
48 alleles are reported.
The phenotypes of these alleles are annotated with 25 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; adult segment; rhabdomere R7; mouthpart; rhabdomere; cell projection; integumentary plate.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: DDHD; HAD-like domain; LNS2, Lipin/Ned1/Smp2; Phosphatidylinositol transfer protein; START-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, during late pupal stages, in stages of adults of both sexes.
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