Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name amos
Flybase description The gene absent MD neurons and olfactory sensilla is referred to in FlyBase by the symbol Dmel\amos (CG10393, FBgn0003270).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.5623 -32.9963 -38.941032 -45.5199 -53.640095 -48.5077 -49.20037 -42.02253
    Affimetrix absolute value 2.957 2.597 2.915 2.882 3.022 2.967 2.939 2.873
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence that it is involved in the biological process: sensory organ boundary specification; sensory organ development.
16 alleles are reported.
The phenotypes of these alleles are annotated with 27 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; peripheral nervous system; antennal segment; adult mesothoracic segment; nervous system; imaginal precursor; abdominal dorsal bipolar neuron dbp; eo support cell; rhabdomere R7; rhabdomere; dorsal thoracic disc.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed within 00-06 hour embryonic stages.
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