Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ry
Flybase description The gene rosy is referred to in FlyBase by the symbol Dmel\ry (CG7642, FBgn0003308).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.3786 -2.5868 -3.687757 -6.4768 -4.913474 -4.8125 -13.28474 -5.525603
    Affimetrix absolute value 6.285 6.252 6.299 5.697 6.492 6.299 4.909 5.825
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: xanthine dehydrogenase activity.
There is experimental evidence that it is involved in the biological process: pyrimidine base metabolic process; determination of adult lifespan; arginine metabolic process; tryptophan metabolic process; glycerophospholipid metabolic process; purine base metabolic process.
355 alleles are reported.
The phenotypes of these alleles are annotated with: Malpighian tubule; pigment cell.
It has one annotated transcript and one annotated polypeptide.
Protein features are: 2Fe-2S ferredoxin, iron-sulphur binding site; Aldehyde oxidase/xanthine dehydrogenase; Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead; Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding; Beta-grasp fold, ferredoxin-type; CO dehydrogenase flavoprotein, C-terminal; CO dehydrogenase flavoprotein-like, FAD-binding, subdomain 2; FAD-binding, type 2; FAD-binding, type 2, subdomain 1; Ferredoxin; Molybdopterin dehydrogenase, FAD-binding; Oxidoreductase, molybdopterin binding site; Xanthine dehydrogenase, small subunit; [2Fe-2S]-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of very low expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in stages of adults of both sexes.
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