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| Gene name | sad | ||||||||||||||||||||||||||||||||||||
| Flybase description | The gene shadow is referred to in FlyBase by the symbol Dmel\sad (CG14728, FBgn0003312). | ||||||||||||||||||||||||||||||||||||
| Expression data along the gut |
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| Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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| Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: ecdysteroid 2-hydroxylase activity. There is experimental evidence that it is involved in the biological process: motor axon guidance; central nervous system development; dorsal closure; ecdysone biosynthetic process; head involution; midgut development. 14 alleles are reported. The phenotypes of these alleles are annotated with 15 unique terms, many of which group under: organ system; multicellular structure; organ system subdivision; nervous system; non-connected developing system; presumptive embryonic/larval nervous system; portion of tissue; cuticle; multi-cell-component structure; integumentary system; cephalopharyngeal skeleton; axon; commissure. It has one annotated transcript and one annotated polypeptide. Protein features are: Cytochrome P450; Cytochrome P450, E-class, group I. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |
