Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Scm
Flybase description The gene Sex comb on midleg is referred to in FlyBase by the symbol Dmel\Scm (CG9495, FBgn0003334).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.7841 -1.9014 -2.95502 -2.6926 -5.55217 -3.977 -2.66621 -4.574834
    Affimetrix absolute value 6.491 6.703 6.621 6.978 6.299 6.58 7.2 6.153
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: gene silencing; germarium-derived female germ-line cyst encapsulation; ovarian follicle cell stalk formation; axonogenesis; neurogenesis.
45 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: larval abdominal segment; adult segment; organ system subdivision; thoracic segment; larval thorax; adult mesothoracic segment; abdominal segment 7; female germline cyst; larval abdominal segment 5; somatic cell; embryonic segment; organ system; axon.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Mbt repeat; Protein of unknown function DUF3588; Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 1; Sterile alpha motif-type; Zinc finger, FCS-type; Zinc finger, MYM-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
.