Flygut: an atlas of the Drosophila adult midgut

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Gene name sev
Flybase description The gene sevenless is referred to in FlyBase by the symbol Dmel\sev (CG18085, FBgn0003366).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -15.5981 -17.8438 -35.033136 -42.6124 -44.93921 -47.4532 -57.62464 -29.208722
    Affimetrix absolute value 4.47 3.508 3.098 2.988 3.3 2.993 2.71 3.406
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein tyrosine kinase activity.
There is experimental evidence that it is involved in the biological process: positive regulation of photoreceptor cell differentiation; positive regulation of R7 cell differentiation; R8 cell fate specification; R7 cell fate commitment.
81 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; nervous system; cuticle; embryonic head; rhabdomere R7; embryonic/larval tracheal system; rhabdomere; cell projection.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin-like fold; LDLR class B repeat; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine-threonine/tyrosine-protein kinase; Six-bladed beta-propeller, TolB-like; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, receptor class II, conserved site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed during late larval stages, in stages of adults of both sexes.
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