Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sgg
Flybase description The gene shaggy is referred to in FlyBase by the symbol Dmel\sgg (CG2621, FBgn0003371).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -50.0858 -30.073 -47.519774 -46.4538 -57.443324 -55.4849 -24.42181 -45.807953
    Affimetrix absolute value 2.78 2.749 2.647 2.876 2.956 2.778 3.967 2.769
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 3 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein kinase activity; kinase activity.
There is experimental evidence for 23 unique biological process terms, many of which group under: biological regulation; anatomical structure development; cellular component organization or biogenesis; regulation of developmental process; learning; multicellular organismal reproductive process; response to chemical stimulus; macromolecule modification; larval chitin-based cuticle development; establishment or maintenance of cell polarity; associative learning; cellular process involved in reproduction; rhythmic process.
161 alleles are reported.
The phenotypes of these alleles are annotated with 46 unique terms, many of which group under: organ system subdivision; adult segment; abdominal ventral denticle belt; organ system; adult mesothoracic segment; nervous system; cuticle; somatic cell; external compound sense organ; larval abdominal segment.
It has 15 annotated transcripts and 15 annotated polypeptides.
Protein features are: Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult male stages.
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