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Gene name | Sh | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Shaker is referred to in FlyBase by the symbol Dmel\Sh (CG12348, FBgn0003380). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: voltage-gated cation channel activity. There is experimental evidence that it is involved in the biological process: regulation of action potential; regulation of circadian sleep/wake cycle, sleep; detection of visible light; proboscis extension reflex; flight behavior; sleep; axon extension; larval locomotory behavior; regulation of synaptic activity. 67 alleles are reported. The phenotypes of these alleles are annotated with 17 unique terms, many of which group under: organ system; organ system subdivision; nervous system; somatic cell; adult; synapse; adult segment; peripheral nervous system; multicellular structure; embryonic/larval neuron; non-connected developing system; adult cuticle; external compound sense organ. It has 11 annotated transcripts and 11 annotated polypeptides. Protein features are: BTB/POZ fold; BTB/POZ-like; Ion transport; Potassium channel, voltage dependent, Kv; Potassium channel, voltage dependent, Kv, tetramerisation; Potassium channel, voltage dependent, Kv1; Voltage-dependent potassium channel. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed during late pupal stages. . |