Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sina
Flybase description The gene seven in absentia is referred to in FlyBase by the symbol Dmel\sina (CG9949, FBgn0003410).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -3.7096 -2.1727 -4.862934 -2.6632 -6.666609 -4.3857 -3.78016 -5.548835
    Affimetrix absolute value 6.52 6.51 5.925 6.979 6.035 6.431 6.655 5.899
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding; protein self-association.
There is experimental evidence that it is involved in the biological process: sensory organ development; regulation of R7 cell differentiation; proteasomal protein catabolic process; ubiquitin-dependent protein catabolic process.
27 alleles are reported.
The phenotypes of these alleles are annotated with 16 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; peripheral nervous system; adult mesothoracic segment; nervous system; presumptive embryonic/larval nervous system; presumptive embryonic/larval peripheral nervous system; sensillum; pigment cell; non-connected developing system.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Seven In Absentia Homolog-type; Seven-in-absentia protein, TRAF-like domain; Seven-in-absentia protein, sina; TRAF-like; TRAF-type; Zinc finger, RING-type; Zinc finger, RING/FYVE/PHD-type; Zinc finger, SIAH-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-06 hour embryonic stages.
.