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Gene name | sisA | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene sisterless A is referred to in FlyBase by the symbol Dmel\sisA (CG1641, FBgn0003411). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding RNA polymerase II transcription factor activity; protein heterodimerization activity. There is experimental evidence that it is involved in the biological process: positive regulation of transcription from RNA polymerase II promoter; posterior midgut development; primary sex determination; anterior midgut development; endoderm development; sex determination. 15 alleles are reported. The phenotypes of these alleles are annotated with: yolk granule; yolk. It has one annotated transcript and one annotated polypeptide. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of no expression detected. Peak expression observed within 00-12 hour embryonic stages. . |