Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name sn
Flybase description The gene singed is referred to in FlyBase by the symbol Dmel\sn (CG32858, FBgn0003447).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -45.1026 -1.6907 -27.085728 -20.972 -49.234272 -45.3587 -50.30759 -18.816354
    Affimetrix absolute value 2.924 6.88 3.427 3.999 3.139 3.064 2.931 4.073
    Affymetric present call in "x" number of chips 0 3 0 3 0 0 0 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; actin filament-based process; organelle organization; post-embryonic organ morphogenesis; establishment or maintenance of cell polarity; wound healing; organ morphogenesis; cuticle pattern formation; localization; microvillar actin bundle assembly; response to stress; sensory organ development.
211 alleles are reported.
The phenotypes of these alleles are annotated with 14 unique terms, many of which group under: organ system; female germline cyst; multicellular structure; sensillum; sense organ; egg; adult segment; external sensillum; organ system subdivision; cuticle; nervous system; wing hair; antennal segment.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Actin cross-linking; Fascin domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression.
Peak expression observed within 06-12 hour embryonic stages, at stages throughout the pupal period.
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