Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name spn-E
Flybase description The gene spindle E is referred to in FlyBase by the symbol Dmel\spn-E (CG3158, FBgn0003483).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.6232 -23.2981 -33.676359 -47.8804 -53.475486 -45.5656 -48.14622 -39.470007
    Affimetrix absolute value 2.938 3.083 3.11 2.818 3.035 3.054 2.966 2.964
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: helicase activity; ATP-dependent RNA helicase activity.
There is experimental evidence for 14 unique biological process terms, many of which group under: cellular component organization or biogenesis; multicellular organismal reproductive process; cellular process involved in reproduction; anatomical structure development; biological regulation; localization; anterior/posterior axis specification; dorsal/ventral axis specification; regulation of cellular macromolecule biosynthetic process; cell cycle; polarity specification of dorsal/ventral axis; regulation of multicellular organismal development.
34 alleles are reported.
The phenotypes of these alleles are annotated with: germline cyst; P granule; oocyte; karyosome; spermatocyte; egg chamber; microtubule; dorsal appendage; synaptonemal complex.
It has one annotated transcript and one annotated polypeptide.
Protein features are: DEAD-like helicase; DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Helicase, C-terminal; Helicase-associated domain; Maternal tudor protein; Tudor domain; Tudor subgroup; Zinc finger, C2H2; Zinc finger, C2H2-like.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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