Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sr
Flybase description The gene stripe is referred to in FlyBase by the symbol Dmel\sr (CG7847, FBgn0003499).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.3083 -29.1045 -39.990413 -46.7513 -60.899927 -50.0264 -49.22234 -48.043448
    Affimetrix absolute value 4.275 2.779 2.86 2.847 2.846 2.919 2.963 2.703
    Affymetric present call in "x" number of chips 3 2 0 1 0 0 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding.
There is experimental evidence that it is involved in the biological process: central nervous system development; ectoderm development; somatic muscle development; germ-band shortening; muscle organ development; epithelial cell migration, open tracheal system; phagocytosis, engulfment.
62 alleles are reported.
The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; embryonic/larval tracheal system; portion of tissue; primordium; adult segment; germ layer; abdominal lateral pentascolopidial chordotonal organ lch5; extended germ band embryo; adult mesothoracic segment.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-18 embryonic stages.
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