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Gene name | Btk29A | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Btk family kinase at 29A is referred to in FlyBase by the symbol Dmel\Btk29A (CG8049, FBgn0003502). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein tyrosine kinase activity. There is experimental evidence for 15 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; multicellular organismal reproductive process; cellular process involved in reproduction; ovarian nurse cell to oocyte transport; gland morphogenesis; learning; determination of adult lifespan; cell cycle; learning or memory; cell cycle process; organ development; biological regulation; embryonic development via the syncytial blastoderm; open tracheal system development; imaginal disc-derived male genitalia development; actin filament-based process; aging. 51 alleles are reported. The phenotypes of these alleles are annotated with 21 unique terms, many of which group under: organ system; organ system subdivision; cephalopharyngeal skeleton; female germline cyst; embryonic foregut; integumentary specialisation; cuticle; portion of tissue; non-connected developing system; taenidial fold; organelle; mouthpart; egg; primordium; spiracle. It has 6 annotated transcripts and 6 annotated polypeptides. Protein features are: Pleckstrin homology domain; Pleckstrin homology-type; Protein kinase, ATP binding site; Protein kinase, catalytic domain; Protein kinase-like domain; SH2 motif; Serine-threonine/tyrosine-protein kinase; Src homology-3 domain; Tyrosine-protein kinase, active site; Tyrosine-protein kinase, catalytic domain; Tyrosine-protein kinase, non-receptor Btk29A; Zinc finger, Btk motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages. . |