Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ss
Flybase description The gene spineless is referred to in FlyBase by the symbol Dmel\ss (CG6993, FBgn0003513).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -41.8912 -32.0556 -43.946175 -48.0074 -65.489188 -53.8404 -49.22228 -46.503815
    Affimetrix absolute value 3.034 2.631 2.726 2.808 2.732 2.817 2.935 2.727
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding.
There is experimental evidence that it is involved in the biological process: regulation of dendrite morphogenesis; antennal development; antennal morphogenesis; leg segmentation.
79 alleles are reported.
The phenotypes of these alleles are annotated with 48 unique terms, many of which group under: organ system subdivision; adult segment; antennal segment; external compound sense organ; appendage segment; adult mesothoracic segment; sensillum; peripheral nervous system; imaginal precursor; larval head segment.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; PAC motif; PAS; PAS fold; PAS fold-3.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of low expression to a trough of extremely low expression.
Peak expression observed within 06-24 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult male stages.
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