Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Su(dx)
Flybase description The gene Suppressor of deltex is referred to in FlyBase by the symbol Dmel\Su(dx) (CG4244, FBgn0003557).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.6545 -0.4119 0.605662 0.3768 -1.487613 -1.0584 -2.71498 -1.541251
    Affimetrix absolute value 5.937 7.515 8.482 8.446 8.211 8.481 7.132 7.715
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Notch binding.
There is experimental evidence that it is involved in the biological process: negative regulation of Notch signaling pathway; receptor internalization; imaginal disc-derived wing margin morphogenesis; imaginal disc-derived wing vein morphogenesis; Notch signaling pathway; lipid storage; imaginal disc-derived leg joint morphogenesis; regulation of protein localization.
13 alleles are reported.
The phenotypes of these alleles are annotated with: wing margin; wing vein L3; leg; wing disc; crossvein; tarsal segment; wing; wing vein.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; HECT; WW/Rsp5/WWP.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages.
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