Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Su(var)2-10
Flybase description The gene Suppressor of variegation 2-10 is referred to in FlyBase by the symbol Dmel\Su(var)2-10 (CG8068, FBgn0003612).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -30.4672 -18.0848 -31.690131 -29.5538 -50.486657 -30.5716 -26.27099 -44.356607
    Affimetrix absolute value 3.503 3.443 3.216 3.503 3.125 3.628 3.848 2.818
    Affymetric present call in "x" number of chips 3 3 3 3 1 3 3 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: DNA binding.
There is experimental evidence that it is involved in the biological process: compound eye development; mitotic cell cycle G2/M transition DNA damage checkpoint; chromosome organization; chromosome condensation; neurogenesis.
25 alleles are reported.
The phenotypes of these alleles are annotated with: eye; polytene chromosome; border follicle cell.
It has 13 annotated transcripts and 13 annotated polypeptides.
Protein features are: DNA-binding SAP; PINIT domain; Zinc finger, MIZ-type; Zinc finger, RING/FYVE/PHD-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-12 hour embryonic stages, in adult female stages.
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