Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tsh
Flybase description The gene teashirt is referred to in FlyBase by the symbol Dmel\tsh (CG1374, FBgn0003866).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.9579 -17.8837 -22.286733 -20.3847 -11.300635 -31.3219 -32.40773 -24.210941
    Affimetrix absolute value 4.868 3.479 3.72 4.061 5.302 3.593 3.539 3.719
    Affymetric present call in "x" number of chips 3 0 0 1 2 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 11 unique biological process terms, many of which group under: anatomical structure development; multicellular organismal process; segment specification; organ development; biological regulation; regulation of cellular macromolecule biosynthetic process; trunk segmentation; embryonic pattern specification; organ morphogenesis; regulation of metabolic process.
54 alleles are reported.
The phenotypes of these alleles are annotated with 56 unique terms, many of which group under: adult segment; organ system subdivision; cuticle; appendage segment; embryonic segment; adult mesothoracic segment; embryonic head; cell cycle; imaginal precursor; cellular component organization or biogenesis; midgut constriction; mouthpart; external compound sense organ; antennal segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.
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