Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name tsl
Flybase description The gene torso-like is referred to in FlyBase by the symbol Dmel\tsl (CG6705, FBgn0003867).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 3.4828 -2.3395 -20.61771 -15.6742 -7.430138 -9.7324 -0.5565 -4.465954
    Affimetrix absolute value 10.199 6.443 3.854 4.443 5.878 5.354 8.298 6.085
    Affymetric present call in "x" number of chips 3 3 0 0 1 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: torso binding.
There is experimental evidence that it is involved in the biological process: torso signaling pathway; terminal region determination; embryonic pattern specification.
30 alleles are reported.
The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: multicellular structure; organ system; organ system subdivision; epithelial furrow; spiracle; embryonic segment; integumentary specialisation; embryonic abdomen; abdominal segment 7; mouthpart; abdominal segment 10; sensillum; larval abdominal segment; abdominal ventral denticle belt; cephalopharyngeal skeleton; late extended germ band embryo.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Membrane attack complex component/perforin (MACPF) domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 06-12 and 18-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period.
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