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Gene name | ptc | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene patched is referred to in FlyBase by the symbol Dmel\ptc (CG2411, FBgn0003892). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein binding; hedgehog receptor activity; lipoprotein particle receptor activity. There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; biological regulation; regulation of biological process; organ development; organ morphogenesis; post-embryonic organ morphogenesis; cellular component organization or biogenesis; multicellular organismal reproductive process; post-embryonic appendage morphogenesis; chemical homeostasis; regulation of response to stimulus; regulation of protein transport; sensory organ development; determination of imaginal disc primordium; multicellular organism reproduction. 179 alleles are reported. The phenotypes of these alleles are annotated with 86 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; abdominal ventral denticle belt; organ system; nervous system; imaginal precursor; presumptive embryonic/larval nervous system; embryonic/larval neuron; commissure. It has one annotated transcript and one annotated polypeptide. Protein features are: Patched; Sterol-sensing domain; Transmembrane receptor, patched. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |