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Gene name | twi | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene twist is referred to in FlyBase by the symbol Dmel\twi (CG2956, FBgn0003900). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: protein heterodimerization activity; protein homodimerization activity; DNA binding. There is experimental evidence that it is involved in the biological process: mesodermal cell fate commitment; muscle fiber development; Malpighian tubule morphogenesis; regulation of striated muscle tissue development; actomyosin structure organization; salivary gland morphogenesis; mesoderm development. 57 alleles are reported. The phenotypes of these alleles are annotated with 32 unique terms, many of which group under: organ system; primordium; adult segment; portion of tissue; late extended germ band embryo; adult mesothoracic segment; non-connected developing system; organ system subdivision; germ layer; adult somatic muscle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain; Twist. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |