Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name usp
Flybase description The gene ultraspiracle is referred to in FlyBase by the symbol Dmel\usp (CG4380, FBgn0003964).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.9706 -2.723 -4.485708 -3.9573 -6.139319 -5.1445 -5.21049 -5.244979
    Affimetrix absolute value 6.104 6.179 6.031 6.408 6.173 6.221 6.211 5.91
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: ecdysteroid hormone receptor activity; protein binding; lipid binding; protein heterodimerization activity; protein homodimerization activity.
There is experimental evidence that it is involved in the biological process: border follicle cell migration; dendrite morphogenesis; neuron development; neuron remodeling; muscle organ development; germ cell development.
22 alleles are reported.
The phenotypes of these alleles are annotated with: dendrite; terminal filament; embryonic/larval anterior spiracle; midgut imaginal island; dorsal multidendritic neuron ddaC; imaginal disc.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Nuclear hormone receptor, ligand-binding; Nuclear hormone receptor, ligand-binding, core; Retinoid X receptor; Steroid hormone receptor; Zinc finger, NHR/GATA-type; Zinc finger, nuclear hormone receptor-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression.
Peak expression observed within 00-06 hour embryonic stages, in adult female stages.
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