Flygut: an atlas of the Drosophila adult midgut

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Gene name vap
Flybase description The gene vacuolar peduncle is referred to in FlyBase by the symbol Dmel\vap (CG9209, FBgn0003969).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.4848 0.2763 -1.58668 -1.5135 -2.113081 -1.4565 -2.92321 -1.89298
    Affimetrix absolute value 7.117 7.548 7.522 7.805 7.692 8.023 7.008 7.343
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: Ras GTPase activator activity.
There is experimental evidence that it is involved in the biological process: mushroom body development; negative regulation of intracellular protein kinase cascade; behavioral response to ethanol; regulation of growth.
26 alleles are reported.
The phenotypes of these alleles are annotated with: optic lobe; nodulus; wing; ellipsoid body; adult brain.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; Pleckstrin homology domain; Pleckstrin homology-type; Ras GTPase-activating protein; Ras GTPase-activating protein, conserved site; Rho GTPase activation protein; SH2 motif; Src homology-3 domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed at stages throughout embryogenesis, during late larval stages, at stages throughout the pupal period, in adult female stages.
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