Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name W
Flybase description The gene Wrinkled is referred to in FlyBase by the symbol Dmel\W (CG5123, FBgn0003997).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -6.1445 -11.0591 -14.366832 -32.4133 -15.962989 -25.7231 -9.1053 -16.280317
    Affimetrix absolute value 5.79 4.156 4.333 3.383 4.764 3.901 5.399 4.235
    Affymetric present call in "x" number of chips 3 3 3 0 3 2 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Its molecular function is unknown.
There is experimental evidence for 19 unique biological process terms, many of which group under: biological regulation; anatomical structure development; positive regulation of programmed cell death; programmed cell death; regulation of apoptosis; gland morphogenesis; cell death; response to light stimulus; cellular component organization or biogenesis; response to red or far red light; post-embryonic organ morphogenesis; embryonic development via the syncytial blastoderm; open tracheal system development; entrainment of circadian clock.
69 alleles are reported.
The phenotypes of these alleles are annotated with 40 unique terms, many of which group under: organ system subdivision; external compound sense organ; adult segment; nervous system; organ system; peripheral nervous system; cephalopharyngeal skeleton; antennal segment; hemocyte; larval head segment.
It has one annotated transcript and one annotated polypeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 06-12 hour embryonic stages, at stages throughout the pupal period.
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