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Gene name | tin | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene tinman is referred to in FlyBase by the symbol Dmel\tin (CG7895, FBgn0004110). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding. There is experimental evidence that it is involved in the biological process: cardioblast differentiation; gonadal mesoderm development; germ cell migration; embryonic heart tube development; pericardial cell differentiation; cardiac cell differentiation; lymph gland development; salivary gland morphogenesis; mesoderm development; cardiac muscle cell differentiation. 58 alleles are reported. The phenotypes of these alleles are annotated with 43 unique terms, many of which group under: organ system; primordium; organ system subdivision; late extended germ band embryo; hypodermal muscle of larval abdomen; A1-7 transverse muscle; midgut constriction; embryonic/larval dorsal vessel; non-connected developing system; nervous system. It has one annotated transcript and one annotated polypeptide. Protein features are: Homeobox; Homeobox, conserved site; Homeodomain-like; Homeodomain-related. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed within 00-06 hour embryonic stages. . |