Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Tm2
Flybase description The gene Tropomyosin 2 is referred to in FlyBase by the symbol Dmel\Tm2 (CG4843, FBgn0004117).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 19.7379 2.1555 -0.424015 2.005 -0.4442 1.9505 7.91472 2.243825
    Affimetrix absolute value 12.697 8.66 8.071 9.366 8.623 9.519 11.52 9.29
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: actin binding.
There is experimental evidence that it is involved in the biological process: heart development.
29 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; myofibril; adult heart; embryonic/larval heart; adult heart chamber; indirect flight muscle.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Tropomyosin.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of low expression.
Peak expression observed during late pupal stages.
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