Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name sc
Flybase description The gene scute is referred to in FlyBase by the symbol Dmel\sc (CG3827, FBgn0004170).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -35.6094 -15.3765 -17.900259 -10.9788 -28.381082 -24.2764 -35.54606 -20.362117
    Affimetrix absolute value 3.273 3.684 4.025 5.044 3.958 3.962 3.404 3.926
    Affymetric present call in "x" number of chips 0 0 0 3 2 3 0 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: sequence-specific DNA binding; protein heterodimerization activity.
There is experimental evidence that it is involved in the biological process: bristle development; sensory organ development; negative regulation of apoptosis; nervous system development; bristle morphogenesis; peripheral nervous system development; sex determination.
184 alleles are reported.
The phenotypes of these alleles are annotated with 63 unique terms, many of which group under: organ system subdivision; adult segment; adult mesothoracic segment; adult external prothorax; postalar bristle; humeral trabecule; eo support cell; anterior vertical bristle; dorsal thoracic disc; antennal segment; portion of tissue.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Achaete-scute transcription factor-related; Helix-loop-helix DNA-binding; Helix-loop-helix DNA-binding domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 00-12 hour embryonic stages, during late larval stages, during early pupal stages.
.