Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ct
Flybase description The gene cut is referred to in FlyBase by the symbol Dmel\ct (CG11387, FBgn0004198).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -48.2038 -31.0792 -42.03327 -43.134 -62.904497 -54.2298 -45.60877 -39.332356
    Affimetrix absolute value 2.84 2.689 2.795 2.96 2.794 2.802 3.056 2.989
    Affymetric present call in "x" number of chips 0 0 0 0 0 1 2 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: DNA binding; sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 12 unique biological process terms, many of which group under: anatomical structure development; cellular component organization or biogenesis; biological regulation; antennal development; multicellular organismal reproductive process; cellular process involved in reproduction; cell cycle; sensory perception of mechanical stimulus; organ development; dendrite morphogenesis; multicellular organism reproduction.
322 alleles are reported.
The phenotypes of these alleles are annotated with 68 unique terms, many of which group under: organ system subdivision; adult segment; antennal segment; synaptic neuropil subdomain; adult mesothoracic segment; spiracle; abdominal lateral pentascolopidial chordotonal organ lch5; multi-cell-component structure; peripheral nervous system; female germline cyst.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: Homeobox; Homeobox, conserved site; Homeodomain protein CUT; Homeodomain-like; Homeodomain-related; Lambda repressor-like, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-18 embryonic stages.
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