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Gene name | Ptp99A | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Protein tyrosine phosphatase 99A is referred to in FlyBase by the symbol Dmel\Ptp99A (CG11516, FBgn0004369). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity. There is experimental evidence that it is involved in the biological process: motor axon guidance; defasciculation of motor neuron axon. 23 alleles are reported. The phenotypes of these alleles are annotated with: intersegmental nerve; abdominal segmental nerve. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Fibronectin type III domain; Fibronectin, type III; Immunoglobulin subtype; Immunoglobulin-like; Immunoglobulin-like fold; Protein-tyrosine phosphatase, active site; Protein-tyrosine phosphatase, receptor/non-receptor type; Protein-tyrosine/Dual-specificity phosphatase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period. . |