Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Klp67A
Flybase description The gene Kinesin-like protein at 67A is referred to in FlyBase by the symbol Dmel\Klp67A (CG10923, FBgn0004379).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -27.295 -19.2993 -24.396734 -31.0096 -25.857628 -25.1893 -38.827 -26.491727
    Affimetrix absolute value 3.696 3.366 3.586 3.454 4.067 3.932 3.282 3.515
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: motor activity.
There is experimental evidence that it is involved in the biological process: sister chromatid biorientation; centrosome separation; male meiosis chromosome segregation; chromosome segregation; mitotic spindle organization; cytokinesis; spindle elongation; microtubule polymerization; spindle assembly; male meiotic chromosome movement towards spindle pole.
14 alleles are reported.
The phenotypes of these alleles are annotated with: spindle microtubule; S2 cell-line; spindle pole; spindle; cytoplasmic microtubule; astral microtubule.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Kinesin, motor domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression.
Peak expression observed within 00-12 hour embryonic stages.
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