Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Galpha49B
Flybase description The gene G protein α49B is referred to in FlyBase by the symbol Dmel\Gα49B (CG17759, FBgn0004435).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.6909 -7.8717 -10.551938 -7.5328 -20.433784 -11.0321 -9.60718 -13.667646
    Affimetrix absolute value 4.864 4.681 4.796 5.5 4.422 5.103 5.316 4.548
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: GTPase activity.
There is experimental evidence that it is involved in the biological process: rhodopsin mediated signaling pathway; activation of phospholipase C activity; phototransduction; negative regulation of compound eye retinal cell programmed cell death; sensory perception of smell; thermotaxis; mucosal immune response; axon midline choice point recognition.
25 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; rhabdomere; photoreceptor cell; eye photoreceptor cell; pCC neuron; wing; adult olfactory receptor neuron Or59b.
It has 8 annotated transcripts and 8 annotated polypeptides.
Protein features are: G protein alpha subunit, helical insertion; G-protein alpha subunit, group Q; Guanine nucleotide binding protein (G-protein), alpha subunit.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-18 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in stages of adults of both sexes.
.