Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name mew
Flybase description The gene multiple edematous wings is referred to in FlyBase by the symbol Dmel\mew (CG1771, FBgn0004456).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -11.6269 -3.2083 -3.804399 -5.4603 -6.301951 -3.7051 -7.05312 -5.554562
    Affimetrix absolute value 4.87 5.981 6.264 5.951 6.126 6.691 5.767 5.818
    Affymetric present call in "x" number of chips 2 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: cell adhesion molecule binding; receptor activity.
There is experimental evidence that it is involved in the biological process: salivary gland boundary specification; axon guidance; axonal defasciculation; cell adhesion; imaginal disc-derived wing morphogenesis; maintenance of epithelial integrity, open tracheal system; sensory perception of smell; muscle attachment; salivary gland morphogenesis.
43 alleles are reported.
The phenotypes of these alleles are annotated with 18 unique terms, many of which group under: organ system subdivision; primordium; presumptive embryonic/larval nervous system; non-connected developing system; multi-cell-component structure; embryonic foregut; organ system; dorsal branch primordium; embryonic/larval visceral branch; female germline cyst; midgut constriction; external compound sense organ; adult segment.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: FG-GAP; Integrin alpha beta-propellor; Integrin alpha chain; Integrin alpha chain, C-terminal cytoplasmic region, conserved site; Integrin alpha-2.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period.
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