Flygut: an atlas of the Drosophila adult midgut

 Mouche Logo lab lemaitre Bbcf logo
Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Fur1
Flybase description The gene Furin 1 is referred to in FlyBase by the symbol Dmel\Fur1 (CG10772, FBgn0004509).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -4.2397 -1.5666 -2.246086 -1.8644 -2.000138 1.0919 -0.5077 -1.951992
    Affimetrix absolute value 6.358 7.005 7.043 7.522 7.785 8.685 8.352 7.316
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: serine-type endopeptidase activity.
It is reported to be involved in the biological process: proteolysis.
28 alleles are reported.
The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum.
It has 6 annotated transcripts and 6 annotated polypeptides.
Protein features are: Furin-like repeat; Galactose-binding domain-like; Growth factor, receptor; Peptidase S8, subtilisin, Asp-active site; Peptidase S8, subtilisin, His-active site; Peptidase S8, subtilisin, Ser-active site; Peptidase S8, subtilisin-related; Peptidase S8/S53, subtilisin/kexin/sedolisin; Proprotein convertase, P; Proteinase inhibitor, propeptide.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression.
Peak expression observed within 00-06 and 12-24 hour embryonic stages, during early pupal stages, in adult female stages.
.