Home | Overview of gut regions | Anatomy | Histology | Transgene expression mapping | Gene expression |
Search expression data by gene: |
Gene name | Mdr49 | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Multi drug resistance 49 is referred to in FlyBase by the symbol Dmel\Mdr49 (CG3879, FBgn0004512). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
|
||||||||||||||||||||||||||||||||||||
Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
||||||||||||||||||||||||||||||||||||
Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled; drug transmembrane transporter activity. There is experimental evidence that it is involved in the biological process: response to hypoxia; response to methotrexate; germ cell migration. 8 alleles are reported. The phenotype of these alleles is annotated with: pole cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like; ATPase, AAA+ type, core. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed within 00-06 hour embryonic stages. . |