Flygut: an atlas of the Drosophila adult midgut

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Gene name Gad1
Flybase description The gene Glutamic acid decarboxylase 1 is referred to in FlyBase by the symbol Dmel\Gad1 (CG14994, FBgn0004516).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -59.2747 -35.3308 -42.534005 -55.3034 -68.417179 -67.4009 -69.74839 -46.66584
    Affimetrix absolute value 2.529 2.492 2.79 2.601 2.696 2.488 2.43 2.707
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: glutamate decarboxylase activity.
There is experimental evidence that it is involved in the biological process: response to mechanical stimulus; synapse assembly; gamma-aminobutyric acid biosynthetic process; neuromuscular junction development; neurotransmitter receptor metabolic process; glutamate catabolic process; larval locomotory behavior.
19 alleles are reported.
The phenotypes of these alleles are annotated with: bouton; neuromuscular junction.
It has 3 annotated transcripts and 3 annotated polypeptides.
Protein features are: Pyridoxal phosphate-dependent decarboxylase; Pyridoxal phosphate-dependent transferase, major domain; Pyridoxal phosphate-dependent transferase, major region, subdomain 1; Pyridoxal phosphate-dependent transferase, major region, subdomain 2; Pyridoxal-phosphate binding site.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during late pupal stages.
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