Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name argos
Flybase description The gene argos is referred to in FlyBase by the symbol Dmel\aos (CG4531, FBgn0004569).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -10.0574 -15.8288 -29.198008 -29.5487 -37.481559 -27.5768 -26.90984 -30.652357
    Affimetrix absolute value 5.112 3.638 3.315 3.505 3.551 3.786 3.836 3.351
    Affymetric present call in "x" number of chips 3 2 1 1 0 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: receptor antagonist activity; epidermal growth factor receptor binding.
There is experimental evidence for 11 unique biological process terms, many of which group under: anatomical structure development; organ development; post-embryonic organ morphogenesis; organ morphogenesis; biological regulation; post-embryonic appendage morphogenesis; sensory organ development; regulation of biological process; ommatidial rotation; cell-cell signaling; appendage development.
97 alleles are reported.
The phenotypes of these alleles are annotated with 87 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; peripheral nervous system; multi-cell-component structure; primordium; abdominal lateral pentascolopidial chordotonal organ lch5; nervous system; egg.
It has one annotated transcript and one annotated polypeptide.
Protein features are: Antagonist of EGFR signalling, Argos.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression.
Peak expression observed within 00-18 hour embryonic stages.
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