Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name Syn
Flybase description The gene Synapsin is referred to in FlyBase by the symbol Dmel\Syn (CG3985, FBgn0004575).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -44.0752 -5.0522 -40.079236 -40.4757 -57.576923 -41.0066 -62.29071 -48.013467
    Affimetrix absolute value 2.948 5.3 2.861 3.055 2.927 3.204 2.596 2.756
    Affymetric present call in "x" number of chips 0 3 0 0 0 2 0 1
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
An electronic pipeline based on InterPro domains suggests that it has the molecular function: ATP binding; ligase activity.
There is experimental evidence that it is involved in the biological process: olfactory learning; memory; response to heat; optomotor response; behavioral response to ethanol; male courtship behavior.
17 alleles are reported.
No phenotypic data is available.
It has 4 annotated transcripts and 4 annotated polypeptides.
Protein features are: ATP-grasp fold, subdomain 1; ATP-grasp fold, subdomain 2; Pre-ATP-grasp fold; PreATP-grasp-like fold; Synapsin; Synapsin, ATP-binding domain; Synapsin, pre-ATP-grasp domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression.
Peak expression observed within 12-24 hour embryonic stages, during early larval stages, during late pupal stages.
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