Flygut: an atlas of the Drosophila adult midgut

Mouche Logo lab lemaitre Bbcf logo

Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name Plc21C
Flybase description The gene Phospholipase C at 21C is referred to in FlyBase by the symbol Dmel\Plc21C (CG4574, FBgn0004611).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -2.1201 -3.6396 -14.556121 -6.0432 -23.916372 -18.9628 -6.3793 -12.959172
    Affimetrix absolute value 7.342 5.789 4.367 5.794 4.196 4.317 5.915 4.674
    Affymetric present call in "x" number of chips 3 3 2 3 2 3 3 3
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
Based on sequence similarity, it is predicted to have molecular function: phosphatidylinositol phospholipase C activity.
There is experimental evidence that it is involved in the biological process: flight behavior.
16 alleles are reported.
The phenotype of these alleles is annotated with: adult olfactory receptor neuron Or59b.
It has 5 annotated transcripts and 5 annotated polypeptides.
Protein features are: C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; EF-hand-like domain; PLC-beta, C-terminal; PLC-like phosphodiesterase, TIM beta/alpha-barrel domain; Phosphoinositide phospholipase C; Phospholipase C, phosphatidylinositol-specific , X domain; Phospholipase C, phosphatidylinositol-specific, Y domain; Phospholipase C, phosphoinositol-specific, EF-hand-like; Pleckstrin homology-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-06 and 18-24 hour embryonic stages, in adult female stages.
.