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Gene name | GluRIIA | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Glutamate receptor IIA is referred to in FlyBase by the symbol Dmel\GluRIIA (CG6992, FBgn0004620). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: glutamate receptor activity. There is experimental evidence that it is involved in the biological process: synaptic transmission; regulation of neurotransmitter secretion; regulation of synaptic activity. 22 alleles are reported. The phenotypes of these alleles are annotated with: t-bar; bouton; neuromuscular junction; embryonic/larval neuromuscular junction; type I bouton; synapse; synaptic vesicle. It has one annotated transcript and one annotated polypeptide. Protein features are: Extracellular ligand-binding receptor; Glutamate receptor, L-glutamate/glycine-binding; Ionotropic glutamate receptor; NMDA receptor. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression. Peak expression observed within 12-24 hour embryonic stages, at stages throughout the larval period, at stages throughout the pupal period, in adult male stages. . |