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Gene name | R | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene Roughened is referred to in FlyBase by the symbol Dmel\R (CG1956, FBgn0004636). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: GTPase activity. There is experimental evidence that it is involved in the biological process: regulation of cell shape; regulation of embryonic cell shape; germ-line stem cell maintenance; dorsal closure; hemocyte migration; cell adhesion; substrate-dependent cell migration, cell extension. 43 alleles are reported. The phenotypes of these alleles are annotated with 23 unique terms, many of which group under: external compound sense organ; organ system subdivision; peripheral nervous system; female germline cyst; nervous system; organ system; germarium; embryonic/larval hemocoel; hemocyte; cuticle. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Small GTP-binding protein domain; Small GTPase superfamily; Small GTPase superfamily, Ras type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages. . |