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Gene name | hh | ||||||||||||||||||||||||||||||||||||
Flybase description | The gene hedgehog is referred to in FlyBase by the symbol Dmel\hh (CG4637, FBgn0004644). | ||||||||||||||||||||||||||||||||||||
Expression data along the gut |
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Intestinal gene expression in different physiological conditions |
Ecc15: flies orally infected with Erwinia carotovora carotovora 15. Pe: flies orally infected with Pseudomonas entomophila. Pe gacA: flies orally infecte with Pseudomonas entomophila gacA. For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe. |
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Gene details (from Flybase) | It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: cell surface binding; protein binding. There is experimental evidence for 25 unique biological process terms, many of which group under: anatomical structure development; biological regulation; localization; organ morphogenesis; sensory organ development; cellular component organization or biogenesis; cellular process involved in reproduction; multicellular organismal reproductive process; organ development; locomotion. 177 alleles are reported. The phenotypes of these alleles are annotated with 190 unique terms, many of which group under: organ system subdivision; adult segment; primordium; late extended germ band embryo; adult mesothoracic segment; ventral nerve cord primordium; organ system; abdominal ventral denticle belt; imaginal precursor; germarium. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Hedgehog, N-terminal signaling domain; Hedgehog/DD-peptidase; Hedgehog/intein hint domain, C-terminal; Hedgehog/intein hint, N-terminal; Intein splice site; Peptidase C46, hedgehog protein; Peptidase C46, hedgehog protein, hint region. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 00-12 hour embryonic stages. . |