Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
Search expression data by gene:
Gene name N
Flybase description The gene Notch is referred to in FlyBase by the symbol Dmel\N (CG3936, FBgn0004647).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -18.8615 -9.7858 -18.098507 -17.4549 -28.444382 -18.314 -30.48948 -25.308351
    Affimetrix absolute value 4.225 4.349 4.003 4.285 3.948 4.405 3.624 3.612
    Affymetric present call in "x" number of chips 2 3 0 3 0 3 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence for 57 unique biological process terms, many of which group under: anatomical structure development; biological regulation; cellular component organization or biogenesis; cellular process involved in reproduction; sensory organ development; multicellular organismal reproductive process; regulation of multicellular organismal development; post-embryonic appendage morphogenesis; organ morphogenesis; regulation of neurogenesis.
678 alleles are reported.
The phenotypes of these alleles are annotated with 227 unique terms, many of which group under: organ system subdivision; adult segment; external compound sense organ; adult mesothoracic segment; nervous system; primordium; embryonic/larval neuron; multi-cell-component structure; late extended germ band embryo; peripheral nervous system.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Ankyrin repeat; Ankyrin repeat-containing domain; EGF; EGF calcium-binding; EGF-like calcium-binding; EGF-like calcium-binding, conserved site; EGF-like region, conserved site; EGF-type aspartate/asparagine hydroxylation site; Epidermal growth factor-like; Epidermal growth factor-like, type 3; Notch; Notch domain; Notch, NOD domain; Notch, NODP domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.
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