Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name fru
Flybase description The gene fruitless is referred to in FlyBase by the symbol Dmel\fru (CG14307, FBgn0004652).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -20.5103 -8.7037 -11.593515 -16.311 -19.099567 -19.7222 -18.53041 -13.398396
    Affimetrix absolute value 4.061 4.591 4.665 4.362 4.518 4.265 4.349 4.603
    Affymetric present call in "x" number of chips 0 0 0 0 0 0 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
It is reported to have molecular function: sequence-specific DNA binding transcription factor activity.
There is experimental evidence for 13 unique biological process terms, many of which group under: mating; behavioral interaction between organisms; anatomical structure development; multicellular organismal reproductive process; multi-organism process; cellular component organization or biogenesis; male courtship behavior, veined wing extension; developmental process involved in reproduction; muscle organ development; central nervous system development.
101 alleles are reported.
The phenotypes of these alleles are annotated with 19 unique terms, many of which group under: organ system subdivision; adult segment; synaptic neuropil subdomain; embryonic/larval neuron; nervous system; antennal segment; adult mesothoracic segment; embryonic/larval glial cell; presumptive embryonic/larval nervous system; gland; external compound sense organ.
It has 14 annotated transcripts and 14 annotated polypeptides.
Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of extremely low expression.
Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages.
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