Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name inaC
Flybase description The gene inactivation no afterpotential C is referred to in FlyBase by the symbol Dmel\inaC (CG6518, FBgn0004784).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -48.2449 -25.867 -32.274059 -47.8559 -58.490398 -57.6491 -48.10441 -39.597296
    Affimetrix absolute value 2.832 2.936 3.204 2.808 2.902 2.721 2.964 2.976
    Affymetric present call in "x" number of chips 0 1 0 0 1 1 0 0
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: protein binding.
There is experimental evidence that it is involved in the biological process: female gonad development; adaptation of rhodopsin mediated signaling; phototransduction; response to ethanol; response to light stimulus; detection of light stimulus involved in sensory perception; cellular component movement; deactivation of rhodopsin mediated signaling; inhibition of phospholipase C activity involved in G-protein coupled receptor signaling pathway; phagocytosis, engulfment.
19 alleles are reported.
The phenotypes of these alleles are annotated with: photoreceptor; eye; retina; ovary; gustatory receptor neuron; ovarian sheath; photoreceptor cell; egg chamber; germarium.
It has one annotated transcript and one annotated polypeptide.
Protein features are: AGC-kinase, C-terminal; C2 calcium-dependent membrane targeting; C2 calcium/lipid-binding domain, CaLB; C2 membrane targeting protein; C2 region; Diacylglycerol/phorbol-ester binding; Protein kinase C, alpha/beta/gamma types; Protein kinase C-like, phorbol ester/diacylglycerol binding; Protein kinase, ATP binding site; Protein kinase, C-terminal; Protein kinase, catalytic domain; Protein kinase-like domain; Serine/threonine-protein kinase domain; Serine/threonine-protein kinase, active site; Serine/threonine-protein kinase-like domain.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of no expression detected.
Peak expression observed during late pupal stages, in adult male stages.
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