Flygut: an atlas of the Drosophila adult midgut

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Home Overview of gut regions Anatomy Histology Transgene expression mapping Gene expression
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Gene name ph-p
Flybase description The gene polyhomeotic proximal is referred to in FlyBase by the symbol Dmel\ph-p (CG18412, FBgn0004861).
Expression data along the gut
    Crop Cardia/R1 R2 R3 R4 R5 Hindgut Full gut
    Ratio gene/RPL42 -5.3712 -2.7963 -6.557708 -4.3412 -11.336426 -5.5897 -4.81381 -10.240338
    Affimetrix absolute value 6.018 6.145 5.522 6.275 5.352 6.094 6.325 5.155
    Affymetric present call in "x" number of chips 3 3 3 3 3 3 3 2
Intestinal gene expression in different physiological conditions
Ecc15: flies orally infected with Erwinia carotovora carotovora 15.
Pe: flies orally infected with Pseudomonas entomophila.
Pe gacA: flies orally infecte with Pseudomonas entomophila gacA.
For methods and description, see Buchon et al. 2009, Cell Host Microbe, and Chakrabarti et al. 2012, Cell Host Microbe.
Gene details (from Flybase) It is a protein_coding_gene from Drosophila melanogaster.
There is experimental evidence that it has the molecular function: chaperone binding; protein binding; chromatin binding.
There is experimental evidence that it is involved in the biological process: central nervous system neuron development; gene silencing; germarium-derived female germ-line cyst encapsulation; ovarian follicle cell stalk formation; response to ecdysone; syncytial blastoderm mitotic cell cycle.
48 alleles are reported.
The phenotypes of these alleles are annotated with 20 unique terms, many of which group under: adult segment; organ system subdivision; organ system; germarium; female germline cyst; portion of tissue; metatarsus; adult mesothoracic segment; germarium region 3; adult external prothorax; larval abdominal segment; external compound sense organ.
It has 2 annotated transcripts and 2 annotated polypeptides.
Protein features are: Sterile alpha motif domain; Sterile alpha motif homology; Sterile alpha motif, type 1; Sterile alpha motif, type 2; Sterile alpha motif-type; Zinc finger, FCS-type.
Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression.
Peak expression observed within 00-12 hour embryonic stages.
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